Since 2019, the world has been faced with the outbreak of different diseases. These diseases have been spreading at a fast pace, and affect a number of people across the world. After the outbreak of the COVID-19 pandemic in 2019, monkeypox (a viral zoonotic disease that can spread from animals to humans and from one human to another) an infectious disease has resurfaced across the world since its first discovery in 1958, in Copenhagen (Denmark). According to the World Health Organization(WHO), since May 2022 cases of monkeypox have been reported from 12 member states where the disease is not endemic (regularly found among particular people or in certain areas). In South Africa, the first case of monkeypox has been identified through laboratory testing at the National Institute for Communicable Diseases (NICD) on 22 June 2022.